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A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

NCT05109390 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2021-11-05

No results posted yet for this study

Summary

This was a 3-part study with each part being an open-label, fixed-sequence, 2-period study in healthy adult participants.

Conditions

  • Healthy

Interventions

DRUG

Danicopan

Oral tablet.

DRUG

Cyclosporine

Oral capsule.

DRUG

Tacrolimus

Oral capsule.

DRUG

Calcium Carbonate

Chewable tablet.

DRUG

Aluminum/Magnesium Hydroxide/Simethicone

Chewable tablet.

DRUG

Omeprazole

Oral, delayed-release capsule.

Sponsors & Collaborators

  • Achillion, a wholly owned subsidiary of Alexion

    collaborator INDUSTRY

  • Alexion Pharmaceuticals, Inc.

    lead INDUSTRY

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-07-27
Primary Completion
2018-10-17
Completion
2018-10-17
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05109390 on ClinicalTrials.gov