MedTrace Logo

Drug/Drug Interactions With F901318

NCT03095547 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL

Last updated 2017-11-01

No results posted yet for this study

Summary

Study of interactions between F901318 and multiple doses of posaconazole and pantoprazole and single doses of cyclosporine A and tacrolimus in healthy subjects. Pharmacokinetic (PK) profiles, safety and tolerability will be assessed.

Conditions

  • Invasive Aspergillosis

Interventions

DRUG

cyclosporine A

Pharmacokinetic assessment Area Under the plasma concentration: time Curve (AUC) 0-t

DRUG

Posaconazole

Pharmacokinetic assessment AUC 0-tau

DRUG

Pantoprazole

Pharmacokinetic assessment AUC 0-tau

DRUG

F901318

Pharmacokinetic assessment AUC 0-tau

DRUG

Tacrolimus

Pharmacokinetic assessment AUC 0-t

Sponsors & Collaborators

  • Bio-Kinetic Europe, Ltd.

    collaborator INDUSTRY

  • F2G Biotech GmbH

    lead INDUSTRY

Principal Investigators

  • David Bell, MD · BioKinetic Europe

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-05-31
Primary Completion
2017-07-31
Completion
2017-10-31

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03095547 on ClinicalTrials.gov