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Quantitative Electroencephalogram and Bispectral Index Brain Mapping During Propofol vs Sevoflurane General Anesthesia

NCT05102422 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2021-11-01

No results posted yet for this study

Summary

General anesthesia interferes with the whole cerebral cortex at different levels. The goal was to investigate the impact of general anesthesia on different regions of the cerebral cortex by recording the brain's electrophysiological activity using QEEG and BIS during general anesthesia for 40 patients undergoing orthopedic surgeries under general anesthesia to see whether our hypothesis, that there is a topographically-dependent impact of general anesthesia on different regions of the cerebral cortex, is valid or not. The patients were randomly divided into 2 groups of 20 patients to compare the effect on the brain function monitoring (QEEG vs BIS) of the intravenous anesthesia (propofol) with the halogenated anesthesia (sevoflurane). And finally, we compared the two brain function monitoring techniques, BIS and QEEG.

Conditions

  • Neurophysiology

Interventions

DRUG

Propofol 1 % Injectable Suspension

Induction and maintenance of general anesthesia using the intravenous anesthetic

DRUG

Sevoflurane inhalant product

Induction and maintenance of general anesthesia using the inhaled anesthetic sevoflurane

Sponsors & Collaborators

  • Pierre Pandin

    lead OTHER

Principal Investigators

  • Pierre Pandin, MD · H.U.B Erasme

Eligibility

Min Age
18 Years
Max Age
87 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-08-21
Primary Completion
2009-12-15
Completion
2009-12-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05102422 on ClinicalTrials.gov