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Evaluation of Remineralization Potential of Self Assembling Peptide Combined With Fluoride

NCT05094492 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 58

Last updated 2021-10-26

No results posted yet for this study

Summary

Self-assembling peptide (P11-4) exhibited an outstanding ability for biomimetic re-mineralization of incipient enamel carious lesions. It creates a 3D matrix within the subsurface of carious lesions, allowing de novo formation of Hydroxyapatite crystals, thus enabling guided enamel regeneration of the demineralized enamel structure. Addition of fluoride to P11-4 may have a synergistic effect on the remineralization potential.

Conditions

  • Caries; Initial

Interventions

COMBINATION_PRODUCT

Curodont Repair Fluoride Plus

P11-4 self assembling peptide combined with fluoride

OTHER

Bifluorid 10 fluoride varnish

5% Sodium Fluoride varnish (equal to 22,600 ppm fluoride)

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Omar O Shaalan, PhD · Lecturer, Conservative Dentistry Department, Faculty of Dentistry, Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-30
Primary Completion
2022-04-30
Completion
2022-06-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05094492 on ClinicalTrials.gov