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Multicenter Study on Organ Acquisition Costs in the Post Re-Allocation Era: Liver Transplantation

NCT05087550 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 186

Last updated 2026-03-24

No results posted yet for this study

Summary

Organ procurement organizations (OPO) have increased organ recovery efficiency and yield and have also reduced organ acquisition charges. The new liver allocation policy came into effect in February 2020 and aims to increase access to organs for waitlist candidates with the greatest severity of illness. The urgent change was driven by the perception that patients were dying because of arbitrary boundaries and inequitable access. Critics of the new policy have highlighted the potential cost implications particularly at an OPO level. A study of five OPOs throughout the United States highlighted an increase in costs ranging from 43% - 206% despite the same volume of livers transplanted. The main reason for the cost appears to lie in organ handling and transport. This mirrors the findings of Puri and colleagues who acknowledged changes to lung transplantation at Barnes Jewish Hospital in the pre- and post-policy eras and reported a substantial decline in local donors. The new lung system has also resulted in a higher organ discard rate and ultimately higher costs. Such data has generated meaningful discussions regarding optimizing organ allocation polices, however, data from individual transplant centers is lacking in the literature. Changes at a transplant center level relating to recipient costs are likely impacted by the new policy, which could be related to patient travel, accommodation, work up etc.

Conditions

  • Liver Transplant

Interventions

PROCEDURE

Liver Transplantation

Patients who underwent liver transplantation at Methodist Dallas Medical Center

Sponsors & Collaborators

  • Washington University School of Medicine

    collaborator OTHER

  • Methodist Health System

    lead OTHER

Principal Investigators

  • Alejandro Mejia, MD · The Methodist Hospital Research Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-13
Primary Completion
2023-06-30
Completion
2023-08-09

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05087550 on ClinicalTrials.gov