Levosimendans Pharmacokinetics in Intensive Care Patients. An Observational Study.
NCT05076864 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 12
Last updated 2021-10-13
Summary
Evaluation of the pharmacokinetics of levosimendan and its metabolites in intensive care patients with normal, reduced and dialysis supported renal function.
Conditions
- Pharmacokinetics
- Metabolites
- Intensive Care
- Renal Failure
- Acute Kidney Injury
Interventions
- OTHER
-
No intervention
No intervention
Sponsors & Collaborators
-
Karolinska University Hospital
collaborator OTHER - lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-01-01
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- Sweden
Study Locations
More Related Trials
-
Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function
NCT00698464 ·Status: COMPLETED ·Phase: PHASE1
-
International, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia
NCT02449044 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196
NCT04867941 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics (Drug Levels in Blood) of BMS-986165 When Taken as Various Solid Tablet Prototypes by Healthy Participants
NCT04249284 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Drug Levels, Safety, and Tolerability of BMS-986036 in Participants With Normal Liver Function and Participants With Moderate and Severe Liver Impairment
NCT04634149 ·Status: COMPLETED ·Phase: PHASE1
-
Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.
NCT03212131 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Pharmacokinetics of BAL8728 After a Single Dose of Pyridinylmethyl-14C-Labeled Isavuconazonium Sulfate in Healthy Male Subjects
NCT02059590 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects
NCT03440424 ·Status: COMPLETED ·Phase: PHASE1
-
The Impact of Renal Impairment on the Pharmacokinetic and Pharmacodynamic of LEO 27847
NCT01141179 ·Status: COMPLETED ·Phase: PHASE1
-
Study of NST-6179 in Healthy Subjects
NCT05181085 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics of MP-3180 in Healthy Volunteers
NCT02098174 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment
NCT05112419 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics and Metabolism of [14C] BMS-986231 in Healthy Male Participants
NCT03210909 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Pharmacokinetics (Drug Levels and Metabolism), Safety, and Tolerability of BMS-986259 in Participants With Various Levels of Kidney Function
NCT04237831 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011
NCT02431481 ·Status: COMPLETED ·Phase: PHASE1
-
Multiple Dose Pharmacokinetics of LCZ696 and Its Metabolites in Subjects With Severe Renal Impairment vs. Matched Healthy Subjects With Normal Renal Function
NCT01569828 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Pharmacokinetics of HSK16149 in Subjects With Renal Impairment
NCT05916573 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics and Safety Study of Levornidazole Disodium Phosphate for Injection in Subjects With Renal Impairment and Normal Renal Impairment
NCT07033182 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Pharmacokinetics of PCI-32765 in Participants With Varying Degrees of Hepatic Impairment
NCT01767948 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Study of BKM120 in Subjects With Hepatic Impairment
NCT01727128 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants
NCT00819468 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function
NCT01569815 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy, Pharmacokinetics and Safety of Org 25969 in Subjects With Normal or Impaired Renal Function (19.4.304)(P05948)(COMPLETED)
NCT00482599 ·Status: COMPLETED ·Phase: PHASE3
-
A Pharmacokinetic Study of CKD-501 in Patients With Impaired Hepatic Function
NCT02005744 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction
NCT01708889 ·Status: COMPLETED ·Phase: PHASE1