Clinical Value of Next Generation Sequencing in Chinese Childhood Solid Tumors
NCT05076071 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2021-10-13
Summary
Samples of 200 patients with pediatric malignant solid tumors will prospectively be collected. Selected samples are sufficient for next generation sequencing(NGS) and available for follow-up information. Multi-omics techniques such as DNA and RNA panel will be used to study driver genes for the development of malignant solid tumors in children, and to explore the pathogenic mechanism. The aim of this study is to explore new biomarkers for the diagnosis and treatment for childhood malignant solid tumors.
Conditions
- Pediatric, Solid Tumors, NGS
Interventions
- GENETIC
-
NGS
Next Generation Sequencing
Sponsors & Collaborators
-
Yizhuo Zhang
lead OTHER
Eligibility
- Min Age
- 0 Years
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-06
- Primary Completion
- 2023-07-06
- Completion
- 2023-08-06
Countries
- China
Study Locations
More Related Trials
-
Studying Genes in Samples From Younger Patients With Rhabdomyosarcoma
NCT01585376 ·Status: COMPLETED
-
Marker Assisted Selective ThErapy in Rare Cancers: Knowledge Database Establishing registrY Asia
NCT05217407 ·Status: RECRUITING
-
Molecular Epidemiology of Pediatric Germ Cell Tumors
NCT05564026 ·Status: RECRUITING
-
Molecular Analysis Of Solid Tumors
NCT01050296 ·Status: RECRUITING
-
Genomics and Prognosis in GI Cancers
NCT05767697 ·Status: RECRUITING
-
Molecular Profiling and Molecular Labeling of Inflammatory Myofibroblastic Tumor
NCT04572594 ·Status: UNKNOWN
-
Studying Genes in Samples From Younger Patients With Adrenocortical Tumor
NCT01528956 ·Status: COMPLETED
-
Diagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Sensitivity Genetic Analysis Techniques
NCT07035587 ·Status: RECRUITING
-
Prospective Multi-omics Observational Study of Gynecological Rare Pathological Tumors
NCT05985941 ·Status: NOT_YET_RECRUITING
-
Detection of CTC and ctDNA in the Diagnosis of Metastasis in Gastric Cancer
NCT05208372 ·Status: UNKNOWN
-
Retrospective WGS Study
NCT06820294 ·Status: ENROLLING_BY_INVITATION
-
Cancer Genome Analysis
NCT01458704 ·Status: UNKNOWN
-
Identifying MSI Status From ctDNA in Chinese Patients With Refractory Advanced Solid Tumors
NCT03596593 ·Status: UNKNOWN ·Phase: NA
-
Studying Tumor Samples From Young Patients With Neuroblastoma
NCT00907920 ·Status: COMPLETED
-
Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer
NCT04903782 ·Status: RECRUITING
-
Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1
NCT01430637 ·Status: COMPLETED
-
The Role of Glycosyltransferases in the Oncogenesis of Neuroblastoma
NCT01058798 ·Status: COMPLETED
-
Liquid Biopsy in Monitoring the Therapeutic Efficacy of Targeted Therapy in Advanced/Metastatic Gastric Cancer
NCT02610218 ·Status: UNKNOWN
-
Detection of G-quadruplex DNA Methylation in Cancer
NCT06537063 ·Status: WITHDRAWN
-
Establishment and Application of 3-Dimensional (3-D) Cell Culture Model of Clinical Circulating Tumor Cells (CTCs)
NCT05623748 ·Status: COMPLETED
-
Studying Gene Expression in Tissue Samples From Patients With Acute Myeloid Leukemia
NCT01057095 ·Status: COMPLETED
-
Biomarkers in Young Patients With Neuroblastoma
NCT01169376 ·Status: COMPLETED
-
Study on Dynamic CtDNA Analysis in Pediatric Soft Tissue Sarcoma
NCT05778955 ·Status: UNKNOWN
-
Early Detection of Gastric Cancer Using Plasma Cell-free DNA Fragmentomics
NCT05269056 ·Status: UNKNOWN
-
Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric Cancer
NCT05336058 ·Status: COMPLETED