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Pulmonary Aspergillosis in Tuberculosis Patients

NCT05045391 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-04-04

No results posted yet for this study

Summary

Pulmonary tuberculosis (PTB) is the most common cause of lung destruction, contributing to coinfections development, and Aspergillosis spp. is one of the most important. Diagnosis of chronic pulmonary aspergillosis (CPA) in PTB patients is difficult due to similarity of clinical and radiological data, especially in resource-constrained settings. Differentiation of PTB patients with singling out a group with a higher Aspergillus IgG level during the initial examination will help physicians to orient to further examination of CPA.

Objectives: to determine the prevalence of aspergillosis in Koch's bacillus-positive and Koch's bacillus-negative PTB patients and antifungal resistance of Aspergillus species isolates in Central Asia countries.

Conditions

  • Pulmonary Tuberculoses
  • Aspergillosis
  • Old Tuberculosis
  • Active Tuberculosis
  • Chronic Pulmonary Aspergillosis

Interventions

DIAGNOSTIC_TEST

Aspergillus IgG detection

Aspergillus IgG will be detected among pulmonary tuberculosis patients. 5 ml of vein blood will be collected for ELISA.

Sponsors & Collaborators

  • Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan

    lead OTHER_GOV

Principal Investigators

  • Abdurakhim Toychiev, MD, PhD · Research institute of epidemiology, microbiology and infectious diseases

Eligibility

Min Age
19 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2025-12-31
Completion
2030-12-31

Countries

  • Uzbekistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05045391 on ClinicalTrials.gov