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Immunocompetent Versus Immunocompromised Tuberculosis (TB) Patients

NCT06709157 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2024-11-29

No results posted yet for this study

Summary

Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the top 10 causes of mortality worldwide. It is estimated that in 2017, 10 million people were infected with TB, and 1.6 million died from the disease, including 0.3 million people with human immunodeficiency virus (HIV) infection . TB remains the primary killer of HIV-positive individuals. TB incidence is falling at about 2% per year . Airborne transmission of M. tuberculosis typically causes TB infection in both immunocompetent and immunocompromised hosts and the disease is symptomatic and contagious .

Conditions

Interventions

DIAGNOSTIC_TEST

P24 antigens and antibody

estimation of antigens and antibodies to diagnose HIV

DIAGNOSTIC_TEST

zeihl - Nelsen stain

staining sputum from patients with HIV to detect tubercle bacilli

DIAGNOSTIC_TEST

culture on Lowenstein jensen media

spenciem will be inoculated on LJ media and kept for 2-8 weeks, to see small white colonies

DIAGNOSTIC_TEST

Molecular detection of antibiotic resistance

to see the pattern of antibiotic resistance of tubercle bacilli

Sponsors & Collaborators

  • Sohag University

    lead OTHER

Principal Investigators

  • Noha S Shafik, Lecturer · Sohag university, Faculty of medicine

  • Asmaa T Mostafa, Lecturer · Sohag university, Faculty of Medicine

  • Ebtisam M Gad, Lecturer · Sohag university, Faculty of Medicine

  • Mona M Abdelrahman, Lecturer · Sohag university, Faculty of Medicine

  • Dina H Mohamed, Lecturer · Sohag university, Faculty of medicine

Eligibility

Min Age
16 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-10
Primary Completion
2024-12-20
Completion
2025-06-01

Countries

  • Egypt

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06709157 on ClinicalTrials.gov