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ACT-Measurement at Different Location During Left Atrial Ablation Procedures

NCT05040035 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 190

Last updated 2021-09-10

No results posted yet for this study

Summary

Ablation of atrial fibrillation is standard therapy for symptomatic patients or patients with severely reduced systolic left ventricular ejection fraction. Complications of the procedure are ischemic thrombembolic stroke. Therefore periprocedural treatment with heparin is administered to acchieve a therapeutic anticoagulation. The efficacy of anticoagulation is measured by active-clotting time (ACT) which is measured with blood drawn mostly from the V. femoralis.

Despite controlled anticoagulation periprocedural stroke is published with an incidence of up to 2% and asymptomatic cerebral embolization from 2% to 15%.

The ACT-Trial has two aims:

1. Analysis of the influence of the localization of blood drawing on the measured ACT: blood from central venous line, from LA and from LAA.
2. Dependency of the ACT measured in the blood of the LAA with regard to anatomic und functional LAA-measurements.

Patients will be included scheduled for left atrial ablation procedure and will be divided in two groups: atrial fibrillation at time of procedure and sinus rhythm at time of procedure.

Conditions

Interventions

DIAGNOSTIC_TEST

ACT measurement

Measurement of active clotting time (ACT)

Sponsors & Collaborators

  • Internistisches Klinikum Munchen Sud

    lead OTHER

Principal Investigators

  • Clemens Jilek, MD · Internistisches Klinikum Munchen Sud

  • Thorsten Lewalter, Prof · Internistisches Klinikum Munchen Sud

Eligibility

Min Age
19 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-26
Primary Completion
2022-09-01
Completion
2022-10-01

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05040035 on ClinicalTrials.gov