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Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude

NCT05037032 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2023-04-26

No results posted yet for this study

Summary

Sleep at altitude is often poor. The purpose of this study is to evaluate the effects of a single dose of the opioid antagonist, naltrexone, on sleep quality and periodic breathing after rapid ascent to \~3800m altitude.

Conditions

  • Altitude
  • Sleep Apnea, Central

Interventions

DRUG

Naltrexone Pill

50 mg PO one-time only

DRUG

Placebo

Matching placebo for naltrexone

Sponsors & Collaborators

  • VA Loma Linda Health Care System

    lead FED

Principal Investigators

  • James D Anholm, MD · VA Loma Linda Healthcare System

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-08-08
Primary Completion
2021-10-17
Completion
2021-10-17
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05037032 on ClinicalTrials.gov