Apatinib Combined With Chemotherapy Versus Chemotherapy in Second-line Gastric Cancer Receiving Prior Anti-PD-1 Therapy
NCT05029453 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2021-08-31
Summary
The study is a multicenter, open-label, randomized controlled clinical study. The purpose of the study is to evaluate the efficacy and safety of apatinib combined with chemotherapy versus chemotherapy in second-line gastric cancer receiving prior anti-PD-1 therapy.
Conditions
- Gastric Cancer
- Randomized Controlled Study
Interventions
- DRUG
-
Apatinib
In experimental group, the drug used with apatinib and chemotherapy.
Sponsors & Collaborators
-
Jiangsu HengRui Medicine Co., Ltd.
collaborator INDUSTRY -
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
lead OTHER
Principal Investigators
-
Tao Zhang, Doctor · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-26
- Primary Completion
- 2022-12-31
- Completion
- 2023-03-03
Countries
- China
Study Locations
More Related Trials
-
Apatinib Combined With Capecitabine Second-line Treatment of Advanced Gastric Cancer: a Single-arm Exploratory Clinical Pilot Trial
NCT03531931 ·Status: UNKNOWN
-
Apatinib Combined With Paclitaxol as Second Line Therapy for Advanced Gastric Cancer.
NCT03144843 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib in Combination With S-1 as First-Line Treatment in Patients With Advanced Gastric Cancer
NCT02525237 ·Status: UNKNOWN ·Phase: PHASE2
-
PD-1 Antibody + Apatinib Mesylate in 2+ Line Serum AFP-elevated Gastric Adenocarcinoma
NCT04006821 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib as the First-Line Therapy in Elderly Locally Advanced or Metastatic Gastric Cancer
NCT03219593 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Apatinib Tablets in the Treatment of Advanced or Metastatic Gastric Cancer
NCT02426034 ·Status: COMPLETED ·Phase: PHASE4
-
Apatinib as Maintenance Therapy After First Line Treatment in Locally Advanced or Metastatic Gastric Cancer
NCT02537171 ·Status: UNKNOWN ·Phase: PHASE3
-
The Clinical Research of Mesylate Apatinib Combined With Docetaxel and S-1 as the First-line Treatment of Metastatic Gastric Cancer
NCT03154983 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib for the Elderly Advanced Gastric Cancer
NCT03104283 ·Status: COMPLETED ·Phase: PHASE2
-
Camrelizumab Combined With Apatinib Versus Apatinib Alone in the Third-line Treatment of Metastatic Gastric Cancer
NCT05342389 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluate the Efficacy of Maintenance Treatment With Capecitabine Plus Apatinib in Advanced Gastric Cancer
NCT03598348 ·Status: UNKNOWN ·Phase: PHASE3
-
The Real World Study of Apatinib for Gastric Cancer Treatment in Anhui Province
NCT03333967 ·Status: UNKNOWN
-
Apatinib Combined With S-1 as Maintenance Therapy for HER-2 Negatived Gastric Cancer
NCT03950141 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Trial to Compare Apatinib Plus Irinotecan Versus Single Irinotecan as Second-line Treatment in AGC or EGJA
NCT03030937 ·Status: UNKNOWN ·Phase: PHASE2
-
The Real World Study of Apatinib for Gastric Cancer Treatment in Henan Province
NCT03478943 ·Status: UNKNOWN
-
Apatinib in Combination With S-1 as Second-Line Treatment in Patients With Advanced Gastric Cancer
NCT03276156 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Apatinib Combined With S1 in Patients With Advanced Gastric Cancer
NCT03271073 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Convernsion Therapy Using S1/Paclitaxel Chemotherapy Plus Apatinib in Unresectable Gastric Cancer
NCT02529878 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Dose Titration in Advanced or Metastatic Gastric Cancer
NCT02764268 ·Status: COMPLETED ·Phase: NA
-
Apatinib Versus Placebo as a Third Line Treatment in Patients With Advanced or Metastatic Gastric Cancer
NCT00970138 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Apatinib Monotherapy Versus Apatinib Combined With Camrelizumab for Third-line Treatment of Metastatic Gastric Cancer
NCT05095636 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase III Study of Apatinib Tablets in the Treatment of Advanced or Metastatic Gastric Cancer
NCT01512745 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Trial of Apatinib Plus Docetaxel in Locally Advanced or Metastatic Gastric or GEJ Adenocarcinoma
NCT03071042 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase II Study of Carelizumab Combined With Irinotecan and Apatinib of Second-line Treatment for Advanced Gastric Cancer
NCT04934618 ·Status: UNKNOWN ·Phase: PHASE2
-
A Clinical Trial of Maintenance Treatment of Apatinib in Advanced Gastric Cancer Patients Have Completed Postoprative Adjuvant Chemotherapy
NCT02776527 ·Status: UNKNOWN ·Phase: PHASE4