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Quantifying Radiation Induced Vaginal Stenosis

NCT05002751 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2025-07-09

No results posted yet for this study

Summary

Radiation (RT) affects the vagina by narrowing, tightening and scarring, termed vaginal stenosis (VS). VS occurs in up to 88% of patients treated with radiation for cervical cancer. VS is not well characterized in measurements. There is a lack of understanding of how short and tight the vagina becomes after RT. This study will use specific measurements of the vagina during the routine physician physical exam after RT in the follow up periods: after RT, 3 months, 6 months, and 12 months using a plastic commercial dilator set and length and width measurements.

In addition, the study use a validated sexual health survey and a specific survey on vaginal dilation preferences to help stop VS after RT.

Conditions

  • Vaginal Stricture
  • Vaginal Stenosis

Interventions

OTHER

UCSD Vaginal Dilator Questionnaire

14 question survey

OTHER

EORTC Sexual Health Questionnaire

22 question survey

Sponsors & Collaborators

Principal Investigators

  • Jyoti Mayadev, MD · University of California, San Diego Moores Cancer Center

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-06
Primary Completion
2026-04-05
Completion
2027-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05002751 on ClinicalTrials.gov