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Effect of Dexamethasone Shortly Before Surgery on the Intraoperative Dose of Remifentanil

NCT05002361 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 94

Last updated 2021-08-12

No results posted yet for this study

Summary

This explorative post hoc analysis included patients randomized in the DEX-2-TKA trial (NCT03506789) who were operated under general anesthesia with remifentanil and propofol. Patients having general anesthesia with sevoflurane were excluded. As the two groups receiving preoperative dexamethasone were identical at the time of outcome assessment, they were merged to one and were compared with placebo.

Conditions

  • Perioperative Pain

Interventions

DRUG

Dexamethasone

24 mg intravenous Dexamethasone (6 ml)

DRUG

Isotonic saline

6 ml of isotonic saline

Sponsors & Collaborators

  • Bispebjerg Hospital

    collaborator OTHER

  • Naestved Hospital

    lead OTHER

Principal Investigators

  • Kasper S Gasbjerg, MD · Naestved Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-14
Primary Completion
2020-03-11
Completion
2020-06-07

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05002361 on ClinicalTrials.gov