Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients
NCT04998864 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3
Last updated 2026-04-16
Summary
The purpose of this study is to evaluate the safety of the Exablate Model 4000 Type 2.0 used as a tool to disrupt the BBB in patients with high grade glioma undergoing standard of care therapy.
Conditions
- Glioma, Malignant
- Glioblastoma
Interventions
- DEVICE
-
Magnetic Resonance guided Focused ultrasound (MRgFUS)
FUS involves the application of acoustic energy at low frequencies from over 1000 individual transducers into distinct body targets.
Sponsors & Collaborators
-
InSightec
lead INDUSTRY
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-25
- Primary Completion
- 2023-07-27
- Completion
- 2023-10-12
Countries
- Italy
- Spain
Study Locations
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