Intrauterine Infusion of GCSF and Reproductive Outcomes in Infertile Women with History of RIF
NCT04998279 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2024-10-01
Summary
Intrauterine infusion of granulocyte colony stimulating factor and reproductive outcomes in infertile women with history of recurrent implantation failure
Conditions
- Recurrent Implantation Failure
- Granulocyte Colony-Stimulating Factor
- Infertility
Interventions
- DRUG
-
Granulocyte Colony-Stimulating Factor
Granulocyte-colony stimulating factors (G-CSF) is synthesized in the reproductive tract naturally, it is a hematopoietic lineage-specific cytokine which is known for its specific effects on the activation of intracellular signaling pathways that are associated with the cell proliferation, differentiation, and stimulation of hematopoietic cells of the neutrophilic granulocyte lineage; which act on macrophages of decidual cells and finally affect implantation
- OTHER
-
placebo
mock test without injection of G-CSF
Sponsors & Collaborators
-
Cairo University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 38 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-01
- Primary Completion
- 2024-08-30
- Completion
- 2024-09-25
Countries
- Egypt
Study Locations
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