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Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery

NCT04995497 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2025-04-09

Study results available
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Summary

Interfascial plane blocks have been developed for analgesia, among which the erector spinae plane (ESP) has gained popularity. The ESP block has been hypothesized to provide truncal analgesia by spread of local anesthetic into the paravertebral space. Recent studies have contested this idea showing unreliability in the spread of the local anesthetic into the paravertebral space.

Conditions

  • Erector Spinae Plane Block
  • Pain Control
  • Post-Operative Pain, Chronic

Interventions

DRUG

Intravenous Administration of Lidocaine Post Cardiac Surgery

Lidocaine will be administered via intravenously. Initial dose will be at 2 mg/kg ideal body weight followed by dosing at 2 mg/kg/hr for 48 hours

DRUG

Administration of Lidocaine Post Cardiac Surgery via ESP Catheter

Lidocaine will be administered via ESP catheter. Initial dose will be at 2 mg/kg ideal body weight split between two catheters followed by dosing at 2 mg/kg/hr for 48 hours

Sponsors & Collaborators

  • Archit Sharma

    lead OTHER

Principal Investigators

  • Archit Sharma, MD · University of Iowa

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-15
Primary Completion
2023-04-07
Completion
2023-04-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04995497 on ClinicalTrials.gov