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Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery

NCT04981067 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2026-04-30

No results posted yet for this study

Summary

The purpose of this study was to determine the minimum effective dose of a local anesthetic for proper anesthesia for popliteal sciatic nerve block under ultrasound guidance in patients undergoing surgery for diabetic foot disease.

Conditions

  • Diabetic Foot
  • Diabetic Neuropathies

Interventions

OTHER

Maintain the concentration of ropivacaine as same as those used in the previous participant

Maintain the same concentration of ropivacaine used in the previous participant with an 89% chance through a random assignment

OTHER

Decrease the ropivacaine concentration by 0.05% from the concentration used in the previous participant

Decrease ropivacaine concentration by 0.05% from the concentration used in the previous participant with an 11% chance through a random assignment

OTHER

Increase the ropivacaine concentration by 0.05% from the concentration used in the previous participant

Increase ropivacaine concentration by 0.05% from the concentration used in the previous participant.

Sponsors & Collaborators

  • Seoul National University Hospital

    lead OTHER

Principal Investigators

  • Seokha Yoo, MD · Seoul National University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
SEQUENTIAL

Eligibility

Min Age
19 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-24
Primary Completion
2027-12-28
Completion
2028-02-29

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04981067 on ClinicalTrials.gov