Patogenic Mutation in 5 Genes
NCT04976439 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 22
Last updated 2021-07-26
Summary
This is a pathogenic mutation profile of colorectal patients specifically in 5 genes, i.e. APC, TP53, PIK3CA, KRAS, and MLH1. Single nucleotide variants identified were synchronized with patients' characteristics.
Conditions
- Colorectal Cancer
- APC Gene Mutation
- TP53 Gene Mutation
- PIK3CA Gene Mutation
- KRAS Mutation-Related Tumors
- MLH1 Gene Mutation
Interventions
- OTHER
-
co-occuring mutation
APC, TP53, PIK3CA, KRAS APC, TP53, PIK3CA, MLH1 APC, TP53, PIK3CA, KRAS, and MLH1 APC, TP53, PIK3CA
Sponsors & Collaborators
-
Dr Cipto Mangunkusumo General Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-01
- Primary Completion
- 2021-06-10
- Completion
- 2021-06-14
Countries
- Indonesia
Study Locations
More Related Trials
-
Genomic Signatures for Patients With Initially Unresectable Colorectal Liver Metastases
NCT06477718 ·Status: COMPLETED
-
Colorectal Adenoma Canceration in FAP
NCT04531930 ·Status: NOT_YET_RECRUITING
-
PET on Surgery for Loco-regionally Recurrent Colorectal Cancer
NCT05924282 ·Status: COMPLETED
-
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients
NCT02022995 ·Status: COMPLETED
-
Outcomes of Neoadjuvant Therapy for Rectal Cancer in a Tertiary Asian Institute
NCT05607186 ·Status: COMPLETED
-
Role of Circulating Tumour DNA Testing in Assessing for Alterations of Primary Anti-EGFR Resistance in RAS/RAF Wild-type Metastatic Colorectal Cancer Patients
NCT05051592 ·Status: UNKNOWN
-
Changes of Low Anterior Resection Syndrome and Balance Ability in Patients With Rectal Cancer.
NCT06006260 ·Status: COMPLETED
-
Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer
NCT04287400 ·Status: RECRUITING
-
New Genes in the Carcinogenesis of Colorectal Cancer
NCT03261752 ·Status: UNKNOWN
-
Constructing a Multimodal Imaging System to Predict the Risk of Heterochronous Metastasis of Rectal Cancer
NCT06293612 ·Status: COMPLETED
-
Characterisation of the Intratumoral Microbiome in Gastric Adenocarcinoma: to a Personalised Medicine
NCT05800236 ·Status: UNKNOWN ·Phase: NA
-
Reasons for Non-reversal of Temporary Stomas After Surgeries of Mid-low Rectal Cancer (NORESTO Study)
NCT06194708 ·Status: RECRUITING
-
Cross-sectional Study of Anorectal Function and Quality of Life in Patients With Middle and Low Rectal Cancer
NCT04697303 ·Status: COMPLETED
-
Metabolism Imaging-genomics for Predicting the Surgical Outcomes of Colorectal Cancer
NCT06614660 ·Status: ACTIVE_NOT_RECRUITING
-
FOS Immunohistochemical Staining of Colorectal Cancer and Its Adjacent Tissues
NCT05698082 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer
NCT05444491 ·Status: ACTIVE_NOT_RECRUITING
-
Clinical Relevance of Major Pathologic Regression for Locally Advanced Rectal Cancer
NCT06879197 ·Status: COMPLETED
-
First-line mCapOX+Cetuximab vs. mFOLFOX6+Cetuximab for Metastatic Left-sided CRC With Wild-type RAS/BRAF Genes
NCT05022030 ·Status: RECRUITING ·Phase: PHASE2
-
Development of a Genome-based Platform for Personalized Treatment in Locally Advanced Rectal Cancer Patients
NCT04738214 ·Status: UNKNOWN
-
Mechanisms of Fate Evolution of Colorectal Adenocarcinoma Metastasis
NCT04714814 ·Status: UNKNOWN
-
Rectal Study: Value of Repeated FDG-PET-CT Scans in Rectal Cancer
NCT00576563 ·Status: COMPLETED ·Phase: NA
-
PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery
NCT00004891 ·Status: COMPLETED ·Phase: NA
-
A Cohort of Predictive Factor of Pathologic Complete Response After Preoperative Neoadjuvant in Rectum Cancer
NCT04443985 ·Status: COMPLETED
-
Fluorescence Molecular Endoscopy and Molecular Fluorescence-guided Surgery in Locally Advanced Rectal Cancer
NCT04638036 ·Status: COMPLETED ·Phase: PHASE1
-
Establishment and Validation of a Predictive Model for the Risk of Colorectal Advanced Adenomas
NCT05152082 ·Status: UNKNOWN