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Characterization of the Efficacy of Furosemide Depending on Albumin Function

NCT04972617 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2022-11-03

No results posted yet for this study

Summary

During this prospective, uncontrolled and non-interventional observational study, the influence of albumin function on the efficacy of furosemide will be investigated. The aim of the study is to provide information on the efficacy of furosemide depending on albumin function.

Conditions

  • Acute Renal Failure
  • Critical Illness

Interventions

DIAGNOSTIC_TEST

albumin function analysis (ABIC)

After centrifugation (10 minutes at 4000 rpm), the plasma is aliquoted and stored at minus 80° C until further analysis. The free as well as the total furosemide concentration is determined by HPLC. In addition to the characterisation of the albumin function by means of the ABiC, these samples can also be used for the determination of the albumin concentration (prerequisite for the determination of the ABiC) and free furosemide concentration as well as for the determination of further parameters relevant for the albumin function.

Sponsors & Collaborators

  • University of Rostock

    lead OTHER

Principal Investigators

  • Steffen Mitzner, MD, PhD · University Hospital Rostock

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-17
Primary Completion
2022-10-31
Completion
2022-10-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04972617 on ClinicalTrials.gov