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Resistant Starch Prebiotic Effects in Chronic Kidney Disease

NCT04961164 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-03-17

No results posted yet for this study

Summary

In patients with Chronic Kidney Disease (CKD), there is a buildup of nitrogenous uremic toxins of gut microbiome origin, which can contribute to uremic symptoms, reduced quality of life, and earlier progression to dialysis. The goal of this project is to investigate whether the consumption of resistant potato starch (RPS) as an adjunctive therapy to current standard of CKD care will reduce uremic toxins and symptoms by altering the gut microbiota in patients with CKD.

Conditions

  • Chronic Kidney Diseases

Interventions

DIETARY_SUPPLEMENT

Resistant Potato Starch, Corn Starch

Consume resistant potato starch at study period 1, then consume corn starch at study period 2.

DIETARY_SUPPLEMENT

Corn Starch, Resistant Potato Starch

Consume corn starch at study period 1, then consume resistant starch at study period 2.

Sponsors & Collaborators

  • University of Manitoba

    lead OTHER

Principal Investigators

  • Dylan Mackay, PhD · University of Manitoba

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-27
Primary Completion
2024-11-20
Completion
2024-11-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04961164 on ClinicalTrials.gov