Safety and Feasibility of Surgery After Conversion Therapy for Locally Advanced and Advanced NSCLC
NCT04945928 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2024-05-24
Summary
Lung cancer is one of the most common malignant tumors worldwide and the mortality ranks first in the world. In recent years, with the development of targeted therapy and immunotherapy, the overall survival of lung cancer patients has improved significantly. However, the inoperable advanced tumor remains the main reason for the poor prognosis of lung cancer. Thus, we aim to carry out this single-arm, prospective study to evaluate the safety and feasibility of surgery after conversion therapy for locally advanced and advanced non-small cell lung cancer.
Conditions
- Pulmonary Neoplasm
- Advanced Cancer
- Locally Advanced Cancer
Interventions
- PROCEDURE
-
Surgery
Participants having been evaluated as operable after receiving first-line treatment (first-line chemotherapy, targeted therapy, immunotherapy, chemotherapy combined with immunotherapy, etc.) will receive surgery.
Sponsors & Collaborators
-
Ruijin Hospital
lead OTHER
Principal Investigators
-
He-Cheng Li, doctor · Ruijin Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-27
- Primary Completion
- 2024-06-05
- Completion
- 2026-06-05
Countries
- China
Study Locations
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