Molecular Profiling of Exosomes in Tumor-draining Vein of Early-staged Lung Cancer
NCT04939324 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2023-04-10
Summary
This is an observational prospective single-center study of 30 patients operated for early-staged non-small cell lung cancer. The main aim is the analysis of molecular profiling of exosome with a sample in tumor-draining vein in order to identify prognostic molecular characteristics associated with cancer recurrence after surgery.
Conditions
- Lung Cancer
- Exosomes
- Non Small Cell Lung Cancer
Interventions
- BIOLOGICAL
-
Blood samples at 2 sites: peripheral vein and tumor-draining vein
D0: surgery (inclusion): oncological lung resection * Blood samples at 2 sites: peripheral vein and tumor-draining vein * Resected tumor analysis Standard clinical and radiological follow-up during 2 years (medical consultation or phone call)
Sponsors & Collaborators
-
University Hospital, Limoges
lead OTHER
Principal Investigators
-
Jérémy Tricard, MD · University Hospital, Limoges
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-21
- Primary Completion
- 2023-08-21
- Completion
- 2024-06-06
Countries
- France
Study Locations
More Related Trials
-
Improving the Early Detection of Lung Cancer by Combining Exosomal Analysis of Hypoxia With Standard of Care Imaging
NCT04629079 ·Status: UNKNOWN
-
Molecular Monitoring of cfDNA by ddPCR in Non-small Cell Lung Cancer Treated by Immunotherapy.
NCT04720339 ·Status: RECRUITING ·Phase: NA
-
Detection of Circulating Endothelial Progenitors Cells (EPCs) in Non-small Cell Lung Cancer (NSCLC)
NCT00826683 ·Status: COMPLETED ·Phase: PHASE3
-
Prediction of Immunotherapeutic Effect of Advanced Non-small Cell Lung Cancer
NCT04427475 ·Status: UNKNOWN ·Phase: NA
-
A Chart Review Study of Adults With Advanced NSCLC
NCT05207423 ·Status: COMPLETED
-
Prospective Multicenter Cohort Study for the Development and Evaluation of Risk Stratification Tools for Lung Cancers and Their Postoperative Recurrences Using Multimodal Clinical, Radiological, Tissue and Longitudinal Biological Phenotyping Among People at Risk of Lung Cancer
NCT07042867 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging
NCT01653002 ·Status: COMPLETED
-
Analysis of Risk Factors of Postoperative Pulmonary Infection in Patients With Esophageal Cancer
NCT05740852 ·Status: COMPLETED
-
Molecular Diagnosis of Lung Cancer Via Bronchoscopy: The Significance of Bronchial Liquid Biopsy (ctDNA and ctRNA)
NCT06228508 ·Status: NOT_YET_RECRUITING
-
Pronostic and Predictive Value of EMT in Localized Lung Cancer
NCT03509779 ·Status: RECRUITING
-
Risk Factors of Medistinal Metastasis in Endoscopic Staging of Lung Cancer
NCT02991924 ·Status: ACTIVE_NOT_RECRUITING
-
Study on Fluids Associated to Lung Cancer
NCT02853006 ·Status: COMPLETED ·Phase: NA
-
Epidemiologic Multicenter Prospective Study in Advanced NSCLC (Non Small Cell Lung Cancer) Patients With PDL1 (Protein Death Ligand 1) Expression.
NCT02785562 ·Status: COMPLETED ·Phase: NA
-
Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer
NCT06244355 ·Status: RECRUITING
-
Genotyping of Ebus-tbna Supernant Cell-free Dna in Nsclc
NCT04624373 ·Status: RECRUITING
-
The Role of Interventional Pulmonology, Microbiota and Immune Response in the Patient With Lung Cancer
NCT05164445 ·Status: COMPLETED ·Phase: NA
-
Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanced NSCLC
NCT05641870 ·Status: UNKNOWN
-
Clinical Study of ctDNA and Exosome Combined Detection to Identify Benign and Malignant Pulmonary Nodules
NCT04182893 ·Status: UNKNOWN
-
The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled Trial
NCT06739421 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Kinetics of Circulating Tumoral Cells in Bronchial Primitive Cancer
NCT03328559 ·Status: COMPLETED ·Phase: NA
-
Identifying Early Lung Cancer Cells in Malignant Pleural Effusion Samples From Patients With Primary Lung Cancer
NCT00897143 ·Status: WITHDRAWN
-
PDL-1 Expression on Circulating Tumor Cells in Non-small Cell Lung Cancer
NCT02827344 ·Status: COMPLETED
-
cDC1 Prognostic and Predictive Role in Non-Small-Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors
NCT04069442 ·Status: WITHDRAWN
-
Prospective Observational Study on ES-SCLC
NCT07173946 ·Status: NOT_YET_RECRUITING
-
Endoscopic Treatment of Bronchial Carcinoid Tumors
NCT03723499 ·Status: COMPLETED