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TMS for Smoking Cessation in PLWHA Cessation in People Living With HIV/AIDS (PLWHA)

NCT04936594 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 9

Last updated 2023-07-13

Study results available
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Summary

The pilot study proposal aims to modulate craving and attentional bias towards smoking cues in 40 people living with HIV/AIDS (PLWHA) using transcranial magnetic stimulation (TMS), with functional MRI (fMRI) brain correlates. TMS is a form of noninvasive brain stimulation and modulates neural activity using tiny doses of focused electricity. For the study, participants would perform two cognitive tasks and neuroimaging before and after the TMS and investigators would compare changes in these paradigms with TMS. The investigators will also get a point of contact urine drug screen before study initiation. The investigators will aim to recruit 20 subjects in each arm of our trial (total of 40) from the BlueGrass HIV Clinic.

Conditions

  • Smoking Cessation
  • HIV
  • Craving

Interventions

DEVICE

iTBS

1800 pulses of iTBS

DEVICE

TMS

MagVenture MagPro x100 device. This will be used as the comparator.

Sponsors & Collaborators

  • Gopalkumar Rakesh

    lead OTHER

Principal Investigators

  • Gopalkumar Rakesh, MD · Assistant Professor, University of Kentucky

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-05-24
Primary Completion
2021-11-24
Completion
2021-11-24
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04936594 on ClinicalTrials.gov