ALPN-202 With PD-1 Inhibition in Advanced Malignancies
NCT04920383 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 29
Last updated 2024-03-01
Summary
This is a cohort-based, open-label dose escalation and expansion study in adults with advanced solid tumors or lymphoma.
Conditions
- Advanced Solid Tumor
- Lymphoma
Interventions
- DRUG
-
ALPN-202
Various doses
- DRUG
-
pembrolizumab KEYTRUDA®
Varies
Sponsors & Collaborators
- collaborator INDUSTRY
-
Alpine Immune Sciences, Inc.
lead INDUSTRY
Principal Investigators
-
Allison Naumovski, Ph.D. · Alpine Immune Sciences
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-22
- Primary Completion
- 2022-11-08
- Completion
- 2023-02-28
- FDA Drug
- Yes
Countries
- United States
Study Locations
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