Embolism in COVID-19 Positive Patients
NCT04910360 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2022-02-15
Summary
Covid-19 outbreak has caused death of millions of people because of not only the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection itself but also infection dependent complications. Abnormalities in thrombotic events leads to some of these complications which eventually result in emboli. The endothelial damage caused by the virus interacting with ACE2 on the host cells leads to the activation of coagulation cascade. Accumulation of byproducts of the cascade might have some roles in embolism inducing risk of organ damage, other life-threatening problems, and even death. To enlighten the factors triggering embolism, the investigators have focused on genetic changes such as polymorphisms and mutations in certain genes in DNA samples coming from intensive care unit (ICU) patients.
Conditions
- COVID-19 Pneumonia
- Embolism
- Genetic Predisposition
Sponsors & Collaborators
-
Afyonkarahisar Health Sciences University
lead OTHER
Principal Investigators
-
Serdar Ceylaner, Assoc. Prof. · INTERGEN Genetics and Rare Diseases Diagnosis Research & Application Center
Eligibility
- Min Age
- 18 Years
- Max Age
- 95 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-03-05
- Primary Completion
- 2021-05-08
- Completion
- 2022-08-30
Countries
- Turkey (Türkiye)
Study Locations
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