Genetic Studies of Early-onset Dementia

NCT04906863 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-04-29

No results posted yet for this study

Summary

The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of 70 years) across all ethnic groups, including Alzheimer's Disease, mild cognitive impairment and other dementias.

Conditions

  • Dementia, Early Onset
  • Alzheimer Dementia (AD)
  • Mild Cognitive Impairment (MCI)
  • Memory Loss

Interventions

GENETIC

Blood draw

Blood draw for identification of genetic variants associated with the development of memory problems

OTHER

Neurocognitive testing

Brief memory test

OTHER

Medical questionnaire

Collection of medical history

Sponsors & Collaborators

  • University of Miami

    collaborator OTHER
  • National Institute on Aging (NIA)

    collaborator NIH
  • Columbia University

    lead OTHER

Principal Investigators

  • Christiane Reitz, MD, PhD · Columbia University

Eligibility

Min Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-09-14
Primary Completion
2028-04-30
Completion
2028-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04906863 on ClinicalTrials.gov