MedTrace Logo

Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain

NCT04902339 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 142

Last updated 2025-04-22

No results posted yet for this study

Summary

The primary aim of this pilot trial is to enhance the efficacy of the Mindfulness-Oriented Recovery Enhancement (MORE) intervention by adding neurofeedback (NF) of the Orbitofrontal Cortex (OFC) as an adjunct to the savoring component of MORE. We hypothesize that the use of NF to train OFC responses during savoring will amplify patients' ability to savor and thereby increase brain responsivity to natural rewards; such enhanced reward responding will in turn be associated with improvements in clinical outcomes (e.g., pain, analgesic use).

Conditions

  • Chronic Pain Syndrome
  • Opioid Use

Interventions

BEHAVIORAL

Mindfulness-Oriented Recovery Enhancement

8 weeks of therapy integrating mindfulness, reappraisal, and savoring skills.

OTHER

Neurofeedback

Near-infrared spectroscopy neurofeedback during savoring practice.

BEHAVIORAL

Supportive Psychotherapy

8 weeks of supportive, process-oriented psychotherapy.

Sponsors & Collaborators

Principal Investigators

  • Eric Garland · University of Utah

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-03
Primary Completion
2025-04-03
Completion
2025-04-03

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04902339 on ClinicalTrials.gov