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Homologous PRP vs Placebo in Knee Osteoarthritis in Over 65 Years Old Patients

NCT04901273 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 204

Last updated 2025-08-03

No results posted yet for this study

Summary

The aim of the study is to compare the 6 months clinical outcome of the treatment with a single injection of Homologous PRP versus single injection of placebo (saline solution) in the infiltrative treatment of knee osteoarthritis in over 65 years old patients. The evaluation will be performed through clinical, subjective and objective assessments.

Conditions

Interventions

PROCEDURE

Homologous PRP injections

Patients will be treated with a single injection of Homologous PRP (5 ml) in the knee joint affected by osteoarthritis.

PROCEDURE

Placebo injection (saline solution)

Patients will be treated with a single injections of saline solution (5 ml) in the knee joint affected by osteoarthritis

Sponsors & Collaborators

  • Istituto Ortopedico Rizzoli

    lead OTHER

Principal Investigators

  • Alessandro Di Martino, MD · Istituto Ortopedico Rizzoli

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-15
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04901273 on ClinicalTrials.gov