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Compression Garments in the Community With POTS

NCT04881318 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-05-07

No results posted yet for this study

Summary

Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that participants wear in their every day lives are effective at improving heart rate and reducing symptoms in POTS. This trial will evaluate the use of commercially available waist-high and abdominal compression garments in adults diagnosed with POTS in a community setting.

Conditions

  • Postural Orthostatic Tachycardia Syndrome

Interventions

OTHER

Waist-High Compression Tights

Waist-high compression tights providing 15-40 mmHg of pressure.

OTHER

Abdominal Compression Garments

Abdominal compression garment compressing the abdomen, buttocks, and upper thighs.

DRUG

Medications that modulate heart rate and blood pressure

Medications that modulate heart rate and blood pressure that participants regularly take. These medications include beta-blockers, midodrine, ivabradine and stimulants.

Sponsors & Collaborators

  • University of Calgary

    lead OTHER

Principal Investigators

  • Satish M Raj, MD MSCI · University of Calgary

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-17
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04881318 on ClinicalTrials.gov