MedTrace Logo

Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD

NCT04879030 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 170

Last updated 2021-05-10

No results posted yet for this study

Summary

The investigators hypothesized that the empirical use of fluoroquinolones together with beta-lactam antibiotics will change their therapeutic success in patients with acute exacerbations of COPD compared to that in patients in whom a single beta-lactam treatment was used. The main goal of this study was to compare the clinical and bacterial success from the use of a combination of beta-lactam and fluoroquinolone antibiotics with that of a single beta-lactam treatment, in adult patients with COPD exacerbations.

Conditions

  • COPD Exacerbation Acute

Interventions

DRUG

Beta-Lactams

The patient was randomized to use beta-lactams antibiotic

DRUG

Fluoroquinolone

The patient was indicated to use a combination of beta-lactams and fluoroquinolones

Sponsors & Collaborators

  • Haiphong University of Medicine and Pharmacy

    lead OTHER

Principal Investigators

  • Phuong TT Nguyen, PhD MD · Haiphong University of Medicine and Pharmacy

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2020-08-30
Completion
2020-12-30

Countries

  • Vietnam

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04879030 on ClinicalTrials.gov