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Which Ventilatory Strategy is Better for Lung in Upper Abdominal Surgeries?

NCT04872361 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 117

Last updated 2021-05-04

No results posted yet for this study

Summary

Ventilated Patients especially those undergoing upper abdominal surgeries are prone to lung atelectasis. They are at risk of adverse effects secondary to inadequate lung ventilation.

Applied PEEP and Recruitment maneuver are thought to enhance lung aeration under general anesthesia which could be assessed by ultrasound.

Conditions

  • Anesthesia Induced Atelectasis

Interventions

PROCEDURE

Low PEEP

Patients will be ventilated with a PEEP of 4 cm H2O and no RMs throughout the study

PROCEDURE

High PEEP

PEEP of 10 cm H2O will be applied

PROCEDURE

High PEEP/RM

PEEP of 10 cm H2O and RM (30 cm H2O for 30 s) immediately after the second lung ultrasonographic examination and repeated every 30 minutes till emergence

DEVICE

Lung ultrasonogrphy assessment

The thorax will divided into 12 quadrants, each of them will be assigned a score of 0-3 as 0, normal lung sliding with fewer than three single B lines 1. three or more B lines 2. coalescent B lines 3. consolidated lung. The LUS (0-36) will be calculated with higher scores indicating more aeration loss

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Aboelnour E Badran, MD · Professor of Anesthesia and Surgical Intensive Care

  • Hanaa M EL- Bendary, MD · Assistant Professor of Anesthesia and Surgical Intensive Care

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-01
Primary Completion
2022-06-30
Completion
2022-10-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04872361 on ClinicalTrials.gov