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Neuralized1 and RGS14 Genes

NCT04865198 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2022-07-26

No results posted yet for this study

Summary

Autism is a broad spectrum neurodevelopmental disease. Some individuals with ADS by high cognitive functions are diagnosed with High Functioning Autism (HFA). In some studies, it has been shown that NEURL1 gene increases learning and memory and RGS14 gene is suppressed them. We aimed to evaluate the differences between the expression levels of these genes between ASD, HFA and healthy controls and the role of these genes in the pathogenesis of ASD. Patients with 20 ASD and 20 HFA, and 20 healthy controls compatible with patient ages were included in this study. Expression of NEURL-1 and RGS14 genes was evaluated by quantitative Real Time PCR (qRT-PCR).

Conditions

Interventions

DIAGNOSTIC_TEST

Neurl1 gene expression

This observational case control study. The gene expression was examined.

DIAGNOSTIC_TEST

RGS14 gene expression

This observational case control study. The gene expression was examined.

Sponsors & Collaborators

  • TC Erciyes University

    lead OTHER

Principal Investigators

  • Hamiyet Eciroğlu, Phd. St. · Alanya Alaaddin Keykubat University

  • Elif F. Şener, Assoc. Prof. · TC Erciyes University

  • Didem B. Öztop, Assoc. Prof. · Ankara University

  • Sevgi Özmen, Assoc. Prof. · TC Erciyes University

  • Dilek Kaan, Phd. · TC Erciyes University

  • Yusuf Özkul, Prof. Dr. · TC Erciyes University

Eligibility

Min Age
2 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-01-10
Primary Completion
2014-08-30
Completion
2014-08-30

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04865198 on ClinicalTrials.gov