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Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.

NCT04860141 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 98

Last updated 2026-02-04

No results posted yet for this study

Summary

This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, severity of pain, the number of analgesics taken, and side effect profiles (e.g. nausea/vomiting, dizziness) at the following intervals, 4 hour, 8 hour, 12 hour, 24, and 72 hour post-procedure.

Conditions

  • Dental Pain and Sensation Disorder
  • Pain, Postoperative

Interventions

DRUG

Gabapentin 600mg

The patient will take gabapentin 600mg 2 hours prior to the procedure

DRUG

Placebo

the patient will take a pill that looks like gabapentin 2 hours prior to the procedure

Sponsors & Collaborators

  • Loma Linda University

    lead OTHER

Principal Investigators

  • Chi Viet, DDS MD PhD · Loma Linda University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-06-16
Primary Completion
2026-12-31
Completion
2026-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04860141 on ClinicalTrials.gov