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Do Adolescents and Adults Differ in Their Acute Response to Cannabis?

NCT04851392 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2021-09-29

No results posted yet for this study

Summary

The acute effects of cannabis may differ between adolescents and adults. Furthermore, these effects may be tempered by the presence of cannabidiol. This double-blind, placebo-controlled, crossover experiment investigates the acute effects of cannabis (with and without cannabidiol) on subjective effects, behavioural responses and neural functioning in 16-17 year-olds and 26-29 year-olds who regularly use cannabis (0.5-3 days per week).

Conditions

  • Cannabis
  • Cannabis Intoxication
  • Cannabis Use
  • Cannabis Dependence
  • Marijuana
  • THC
  • CBD
  • Adolescent Development

Interventions

DRUG

Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)

Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) - inhaled and vaporised cannabis flower

DRUG

Cannabis with THC without CBD

Cannabis with THC without CBD - inhaled and vaporised cannabis flower

DRUG

Placebo cannabis

Placebo cannabis, without THC and without CBD - inhaled and vaporised

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
16 Years
Max Age
29 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-11
Primary Completion
2021-06-16
Completion
2021-06-16

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04851392 on ClinicalTrials.gov