MedTrace Logo

EXtended CriteriA Treatment for LIver Metastases and Heavy Tumour BURden

NCT04840186 · Status: SUSPENDED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 62

Last updated 2024-11-12

No results posted yet for this study

Summary

Patients with multiple colorectal liver metastases that progress on 1st line chemotherapy have a very dismal prognosis, and their options are few. Resections are regularly performed although this is only supported by anecdotal evidence for this patient group. We want to assess whether resections actually confer benefit as compared to 2nd line chemotherapy alone, in a randomized controlled trial.

Conditions

Interventions

PROCEDURE

Liver-resection or ablation

Liver-resection of colorectal liver metastasis. Ablation can be used as adjunct to surgery.

DRUG

2nd line chemotherapy

2nd line chemotherapy. Type of chemotherapy is determined by treating oncologist

Sponsors & Collaborators

  • Oslo University Hospital

    lead OTHER

Principal Investigators

  • Kristoffer Lassen, MD PhD · Oslo University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-23
Primary Completion
2024-12-01
Completion
2026-03-31

Countries

  • Norway

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04840186 on ClinicalTrials.gov