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The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases

NCT04161092 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2024-10-28

No results posted yet for this study

Summary

To evaluate if the addition of liver transplantation primarily utilizing liver grafts from extended criteria donors not utilized for approved indications to conventional treatment of non-resectable/ non-abatable colorectal liver metastases (CLM) increases overall survival compared to best alternative care.

Conditions

Interventions

PROCEDURE

Liver transplantation Ltx

Patients will be treated with Ltx at Sahlgrenska University Hospital, Göteborg, or Karolinska University Hospital, Huddinge.

OTHER

Best alternative care

All available treatments as well as other experimental treatments are tolerated, however no cross-over to other arm will be allowed.

Sponsors & Collaborators

  • Vastra Gotaland Region

    lead OTHER_GOV

Principal Investigators

  • Per G Lindner, MD, PhD · Transplant Institute, Sahlgrenska University Hospital

  • Carl Jorns, MD, PhD · Transplantation Unit, Karolinska University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2029-12-31
Completion
2030-06-30

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04161092 on ClinicalTrials.gov