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Effects of BRS and LRS on Postoperative Acute Kidney Injury

NCT04835038 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 3400

Last updated 2023-04-12

No results posted yet for this study

Summary

1. Title: Effects of Sodium Bicarbonate Ringer's Injection and Sodium Lactated Ringer's Injection on postoperative acute kidney injury in patients undergoing major abdominal surgery: a randomized, controlled, open-label clinical study
2. Objective: To evaluate the effect of BRS and LRS infusion on acute renal injury in patients undergoing major abdominal surgery
3. Primary outcome: Incidence of AKI at 28 days postoperative (defined as acute kidney injury, according to Kidgo 2012 definition and classification).
4. Study Design: Randomized, controlled, open-label clinical study.

Conditions

Interventions

DRUG

Sodium Bicarbonate Ringer's Injection

Intraoperative fluid therapy performed with BRS (Sodium Bicarbonate Ringer's Injection)

DRUG

Sodium Lactated Ringer's Injection

Intraoperative fluid therapy performed with LRS (Sodium Lactated Ringer's Injection)

Sponsors & Collaborators

  • Tongji Hospital

    lead OTHER

Principal Investigators

  • Shiyong Li · Tongji Hospital

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-06-01
Primary Completion
2023-06-30
Completion
2023-08-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04835038 on ClinicalTrials.gov