Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs)

Summary

Harmful alcohol use is a global risk factor for disease, injuries and death. Research on treatment of Alcohol use disorders (AUDs) indicates that different treatment modalities are equally effective, but also that a large group of patients do not change their drinking pattern despite being in treatment. It is assumed that it is not random who benefits from treatment. Thirty to forty percent of outcome variance in treatment is probably explained by patient factors, and we need more knowledge on how different patient factors moderate treatment effects.

Further, clinicians also need more knowledge about selecting patients to different therapies. The present study will investigate how patient factors predict outcome in group treatment of AUDs, and what predicts positive treatment outcomes over time. The study is designed as a quasi-experimental, multi-centre, follow-up study. Patients will be included from Vestfold Hospital Trust, Borgestadklinikken, Blue Cross Clinic, Behandlingssenteret Eina, Blue Cross Clinic and A-senteret, Oslo, Church City Mission. The Project will provide more knowledge about patients seeking treatment for AUDs, and specifically how patient factors predict outcome in group treatment. These results will in turn lead to better selection of treatment modalities, and patients will receive a more effective treatment earlier on.

Main aims: 1) How do patient factors predict outcome in group treatment of alcohol use disorders (AUDs)? 2) Do positive treatment outcomes last over time? Specifically, do the following factors: a) psychiatric comorbidity b) severity of alcohol use pre-treatment c) personality disorders and d) cognitive impairments predict 1) completion of group treatment and 2) positive outcome after 1 year. As an additional aim, we will investigate if the Montreal Cognitive Assessment test (MoCa) is feasible as a brief screening instrument for mild cognitive impairments for AUD patients.

Conditions

• Alcohol Use Disorder (AUD)
• Alcohol Abuse
• Drug Abuse
• Psychiatric Disorder
• Personality Disorders
• Cognitive Deficit
• Cognitive Impairment
• Substance Use Disorders

Sponsors & Collaborators

• Oslo University Hospital

  collaborator OTHER

• Borgestadklinikken, Blue Cross Clinic

  collaborator UNKNOWN

• Behandlingssenteret Eina, Blue Cross Clinic

  collaborator UNKNOWN

• University of Southern Denmark

  collaborator OTHER

• University of New Mexico

  collaborator OTHER

• The Hospital of Vestfold

  lead OTHER

Principal Investigators

• Jens Egeland, Phd · Vestfold Hospital Trust/University of Oslo

Eligibility

Min Age

18 Years

Max Age

90 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2021-02-01

Primary Completion

2026-01-01

Completion

2030-12-31

Countries

• Norway

Study Locations