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Impact of 4 Months of Exercise Changes of Heart Health-related Epigenetic Markers in Healthy, Sedentary Individuals

NCT04791306 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2024-04-04

No results posted yet for this study

Summary

We aim to analyze the impact of a single acute exercise intervention (ergometry) on the expression pattern of specific heart health related miRNAs in healthy, previously sedentary participants, and how this pattern will be changed after 4 months of increasing the weekly physical activity \>150 minutes.

Conditions

  • Sedentary Behavior

Interventions

OTHER

supervised exercise training

Participates perform once a week for 4 months an in-house supervised endurance and strength training.

OTHER

home-based exercise training

Participants are provided with an application for planning and documentation of their physical activity, together with an expert participants plan their physical activities for their home-based training to reach at least 150 min physical activity per week.

Sponsors & Collaborators

  • Ludwig Boltzmann Institute for Digital Health and Prevention

    collaborator OTHER

  • Paracelsus Medical University

    lead OTHER

Principal Investigators

  • Prof. Josef Niebauer, MD PhD MBA · Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2023-03-31
Completion
2024-03-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04791306 on ClinicalTrials.gov