Opicapone Treatment Initiation Open-Label Study
NCT04787965 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 239
Last updated 2022-11-28
Summary
This is an observational study to describe the treatment patterns and clinical outcomes observed with use of ONGENTYS as adjunctive treatment to levodopa/carbidopa in Parkinson's disease patients experiencing "off" episodes with motor fluctuations
Conditions
- Parkinson Disease
Interventions
- DRUG
-
Opicapone
Opicapone as adjunctive treatment to levodopa/carbidopa over a 6-month period
Sponsors & Collaborators
-
Neurocrine Biosciences
lead INDUSTRY
Principal Investigators
-
Olga Klepitskaya, MD, FAAN · Neurocrine Biosciences
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-03-01
- Primary Completion
- 2022-08-04
- Completion
- 2022-08-04
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Post Marketing Observational Study of Activities of Daily Living in Advanced Parkinson's Disease Patients With Early Troublesome Motor Fluctuations and Treated With Duodopa - a Multi-country Study
NCT01747655 ·Status: COMPLETED
-
A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa
NCT00134966 ·Status: COMPLETED ·Phase: PHASE3
-
Early ParkinSon wIth L-DOPA/DDCI and OpicapoNe (EPSILON Study)
NCT04978597 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Safety and Efficacy of Levodopa-carbidopa Intestinal Gel (LCIG) for the Treatment of Non-motor Symptoms in Patients With Advanced Parkinson's Disease
NCT01736176 ·Status: COMPLETED ·Phase: PHASE3
-
Long Term Effectiveness of Levodopa-Entacapone-Carbidopa Intestinal Gel in Participants With Advanced Parkinson's Disease
NCT07313176 ·Status: RECRUITING
-
Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Counteract Dopaminergic Desensitization and Neuropsychiatric Complications in Parkinson's Disease
NCT07151378 ·Status: RECRUITING ·Phase: PHASE3
-
eArly levoDopa With Opicapone in Parkinson's paTients wIth motOr fluctuatioNs.
NCT04990284 ·Status: COMPLETED ·Phase: PHASE4
-
A Pharmacokinetic Study of Levodopa and Carbidopa Intestinal Gel in Subjects With Advanced Parkinson's Disease
NCT01484990 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic Study in Healthy Males
NCT02312232 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of AP-CD/LD in Fluctuating Parkinson's Disease Patients Who Completed IN 11 004
NCT02615873 ·Status: UNKNOWN ·Phase: PHASE3
-
Study to Compare the Effect of Treatment With Carbidopa/Levodopa/Entacapone on the Quality of Life of Patients With Parkinson's Disease. This Study is Not Recruiting in the United States
NCT00143026 ·Status: COMPLETED ·Phase: PHASE4
-
A Pilot Study of a Non-Invasive Neuromodulation Device for Treatment of Parkinson's Disease
NCT02134795 ·Status: TERMINATED ·Phase: NA
-
A Study of Buntanetap in Participants With PD
NCT07284784 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease
NCT00335153 ·Status: COMPLETED ·Phase: PHASE3
-
DESENSITIZE-PD: Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Support Dopaminergic Desensitization in PD
NCT05579379 ·Status: UNKNOWN
-
Assessment of Actigraphy Procedures on the Initiation of an Apomorphine Treatment Delivered Through a Pump to Patients With Parkinson's Disease
NCT03213379 ·Status: UNKNOWN ·Phase: NA
-
Basic and Clinical Studies of Levodopa/Carbidopa/Entacapone in the Treatment of Early Parkinson's Disease
NCT06236230 ·Status: RECRUITING ·Phase: PHASE4
-
Double-blind Placebo Surgery Trial for Treatment of Parkinson's Disease
NCT03347955 ·Status: COMPLETED ·Phase: NA
-
Novel DBS Stimulation Patterns for Treatment of Parkinson's Disease
NCT04799470 ·Status: RECRUITING ·Phase: NA
-
Pedunculo-Pontin Nucleus (PPN) - Deep Brain Stimulation (DBS) in Gait and Balance Disturbance in Parkinson's Disease (PPN-GAB-PARK Study)
NCT00821743 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Efficacy and Safety Proof of Concept Study in Patients With Parkinson's Disease and End-of-dose Wearing-off (COMPOC)
NCT02764125 ·Status: COMPLETED ·Phase: PHASE2
-
Augmenting Effects of L-DOPS With Carbidopa and Entacapone
NCT00547911 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Deep Brain Stimulation to Treat Symptoms of Parkinson's Disease
NCT00552474 ·Status: COMPLETED ·Phase: NA
-
STEM-PD Open Label Extension (OLE)
NCT04799418 ·Status: TERMINATED ·Phase: NA
-
Global REsponsE During iNFusIon of a gEl With LevoDopa/Carbidopa
NCT01754129 ·Status: COMPLETED