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DNA Damage and Oxidative Stress in Hospitalized COVID-19 Patients

NCT04784468 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 135

Last updated 2021-03-09

No results posted yet for this study

Summary

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic challenging health systems worldwide.

While there is a clear correlation between oxidative stress markers and the severity of many viral diseases such as hepatitis C, for SARS-CoV clinical data is limited.

The investigators aim at 1.) investigating DNA damage, oxidative stress, inflammation, and aging markers in COVID-19 patients and compare them with age and gender matched healthy controls and patients with influenza; and 2.) investigating all aforementioned parameters during "cytokine storm" via repeated blood sampling.

Conditions

  • Covid19

Interventions

OTHER

No intervention

Case-control design, one single investigation

Sponsors & Collaborators

  • SMZ-Ost Donauspital

    collaborator OTHER

  • University of Vienna

    lead OTHER

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-11-19
Primary Completion
2021-03-31
Completion
2021-09-30

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04784468 on ClinicalTrials.gov