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DNA Damage in Critically Ill COVID-19 Patients

NCT04772703 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2022-09-27

No results posted yet for this study

Summary

Critically ill patients with COVID-19 are exposed to high oxidative stress which is potential harm to the DNA. Peripheral lymphocytes' DNA will be investigated using the comet assay on changes in oxidative damage to the purine and pyrimidine bases and single-stranded DNA breaks.

Conditions

  • Covid19
  • Organ Failure, Multiple
  • DNA Damage

Interventions

DIAGNOSTIC_TEST

COMET ASSAY

The description in the detailed description of the study

Sponsors & Collaborators

  • University Hospital Hradec Kralove

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-23
Primary Completion
2021-02-28
Completion
2021-02-28

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04772703 on ClinicalTrials.gov