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Relationship Between Diet, Oxidative Stress and Inflammation in Ankylosing Spondylitis

NCT04772976 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 73

Last updated 2021-02-26

No results posted yet for this study

Summary

Ankylosing Spondylitis (AS) is a chronic inflammatory autoimmune disease. The aim of this study is to reveal the relationship between dietary intake, blood total antioxidant capacity and disease activity in individuals with AS. This study will include patients diagnosed with AS who applied to Ankara City Hospital Physical Therapy and Rehabilitation Hospital, and a control group that does not have AS. The sociodemographic characteristics and nutritional habits and 1-day physical activity status of individuals with AS and healthy persons will be recorded. Anthropometric measurements of all individuals (such as height length (cm) and body weight) will be taken. From the height and body weight measurements, the individuals body mass indexes will be calculated. All parts of the questionnaire for individuals included in the research will be filled in by the researcher through face-to-face interview technique. The disease activity score of the individuals in the case group will be evaluated by the physician. Serum biochemical parameters will be taken from the patient files. In the patient information system of the control group, above mentioned blood tests will be recorded from the examinations performed in the last 1 month. Serum total antioxidant and oxidant levels will be measured in a private laboratory with a tube (5 ml) of blood from all individuals. The parameters to be examined in blood samples are specific to the study and their cost will be covered by the researchers.

Conditions

Interventions

OTHER

Observational study, not applicable

Observational study, not applicable

Sponsors & Collaborators

  • Ankara City Hospital Bilkent

    lead OTHER

Principal Investigators

  • Fatma Gul Yurdakul, Assoc.Prof. · Ankara City Hospital, Physical Medicine and Rehabilitation Hospital, Ankara, Turkey

  • Hatice Bodur, Prof. · Ankara City Hospital, Physical Medicine and Rehabilitation Hospital, Ankara, Turkey

  • Evren Yasar, Prof · Ankara City Hospital, Physical Medicine and Rehabilitation Hospital, Ankara, Turkey

  • Nilgun Seremet Kurklu, Asist.Prof. · Akdeniz University, Faculty of Health Sciences, Department of Nutrition and Dietetics

  • Kubra Tel Adiguzel, Asist.Prof. · University of Health Sciences Turkey, Gulhane Faculty of Health Sciences, Nutrition and Dietetics

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-11-16
Primary Completion
2021-01-31
Completion
2021-02-03

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04772976 on ClinicalTrials.gov