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Body Composition and Nutritional Status in Pediatric Patients With Hematological Malignancies

NCT04764695 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 38

Last updated 2024-12-06

No results posted yet for this study

Summary

Introduction: Annually 400,000 children are diagnosed with cancer in the world. Approximately 90% live in low/middle-income countries, with survival rates of 10-30%. In Mexico, children and adolescents' hospital admissions for cancer are mainly leukemias (46%), being acute lymphoblastic leukemia (ALL) the most common. Half of ALL patients have an altered nutritional status at the time of diagnosis. Nutritional assessment is performed using conventional anthropometric measures, which are not sensitive to changes in fat-free mass and fat mass (FFM and FFM). Our objective is to evaluate the body composition and nutritional status in pediatric patients with HM. This is a pre-test/post-test clinical trial. Children 2-14 y olds diagnosed with leukemia, myeloma and lymphoma in any stage of oncological treatment will participate. The nutritional status will be evaluated using questionnaires and body composition. Measurements will occur at the enrrollment of the study and 6 months after.

Conditions

  • Childhood Cancer
  • Child Malnutrition
  • Childhood Obesity

Interventions

DIAGNOSTIC_TEST

D2O dilution technique

Body composition will be measured with the deuterium dilution technique and electrical bioimpedance, as well as anthropometric indicators at the beginning and 6 months later.

Sponsors & Collaborators

  • International Atomic Energy Agency

    collaborator OTHER_GOV

  • Hospital Civil de Guadalajara

    collaborator OTHER

  • Centro de Investigación en Alimentación y Desarrollo A.C.

    collaborator OTHER

  • Universidad de Sonora

    lead OTHER

Principal Investigators

  • Veronica López Teros, PhD · Universidad de Sonora

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
2 Years
Max Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-30
Primary Completion
2024-08-30
Completion
2024-11-30

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04764695 on ClinicalTrials.gov