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Research on the Physiological Characteristics of the Gastrointestinal Tract in Chinese Volunteers

NCT04743726 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2021-02-08

No results posted yet for this study

Summary

The dissolution and absorption of oral drugs in the gastrointestinal tract is a complex process, which is affected by physiological factors such as transporters, metabolic enzymes, gene phenotypes, gastrointestinal diseases, intestinal flora and so on. Therefore, the investigators are planning to collect gastrointestinal mucosa tissues, gastric juice, saliva , feces and blood samples to investigate (1) the activity and abundance of metabolism enzymes/transports in different section of gastrointestinal tract, (2) the composition and physicochemical properties of gastric juice; (3) the distribution and abundance of bacterial in gastrointestinal mucosa, saliva, gastric juice and feces; (4) the composition and content of bile acid in gastrointestinal mucosa, gastric juice and plasma in Chinese volunteers who planning to undergo digestive endoscopy.

Conditions

  • Endoscopy, Gastrointestinal

Sponsors & Collaborators

  • Dongyang Liu

    lead OTHER

Principal Investigators

  • Dongyang Liu · Drug Clinical Trial Center

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-31
Primary Completion
2022-09-30
Completion
2022-09-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04743726 on ClinicalTrials.gov