Study of ON 123300 in Patients With Advanced Cancer
NCT04739293 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2023-12-07
Summary
This study will investigate the safety of the drug ON 123300 at increasing doses to determine the best dose to use in future clinical trials.
Conditions
- Solid Tumors, Adult
Interventions
- DRUG
-
ON123300
ON 123300 hard gelatin capsules
Sponsors & Collaborators
-
Traws Pharma, Inc.
lead INDUSTRY
Principal Investigators
-
Michael E Saunders, MD · Onconova Therapeutics
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-13
- Primary Completion
- 2024-10-31
- Completion
- 2024-10-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors
NCT02298387 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies
NCT01351350 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma
NCT01177397 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of the Safety and Tolerability of Oral Capsule Form of PCI-24781 in Advanced Cancer Patients
NCT00562224 ·Status: COMPLETED ·Phase: PHASE1
-
NUC-3373 in Advanced Solid Tumours
NCT02723240 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of XS-02 Capsules in Patients With Advanced Solid Tumors
NCT06531486 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors
NCT03182257 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of OKI-179 in Patients With Solid Tumors
NCT03931681 ·Status: COMPLETED ·Phase: PHASE1
-
Oral ONC201 in Treating Patients With Advanced Solid Tumors
NCT02250781 ·Status: COMPLETED ·Phase: PHASE1
-
A Dose-Escalation Study of OBP-801 in Patients With Advanced Solid Tumors
NCT02414516 ·Status: UNKNOWN ·Phase: PHASE1
-
L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors
NCT00003430 ·Status: COMPLETED ·Phase: PHASE1
-
A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer
NCT02038699 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Phase 1, Open-label Trial to Determine Safety of OPB-51602 in Subjects With Advanced Cancer
NCT01423903 ·Status: COMPLETED ·Phase: PHASE1
-
ONO-7913 Phase I Study (ONO-7913)
NCT04403308 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study of Oprozomib Administered Orally in Patients With Advanced Refractory or Recurrent Solid Tumors
NCT01129349 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
NCT04541082 ·Status: RECRUITING ·Phase: PHASE1
-
Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors
NCT00820560 ·Status: COMPLETED ·Phase: PHASE1
-
Study of PKI-179 Administered Orally to Subjects With Solid Tumors
NCT00997360 ·Status: WITHDRAWN ·Phase: PHASE1
-
Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)
NCT00670488 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors
NCT03730337 ·Status: COMPLETED ·Phase: PHASE1
-
Safety of ON 01910.Na as a 3-day Infusion in Patients With Advanced Cancer
NCT01538537 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's Lymphoma
NCT01356173 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors
NCT00880308 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability of ODM-203 in Subjects With Advanced Solid Tumours
NCT02264418 ·Status: COMPLETED ·Phase: PHASE1
-
Intratumoral N17350 in Advanced Solid Tumors
NCT07339176 ·Status: RECRUITING ·Phase: PHASE1/PHASE2