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Exploration of the Predictive Marker and Establishment of Predictive Models of Checkpoint Inhibitor Pneumonitis

NCT04734067 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 440

Last updated 2021-08-23

No results posted yet for this study

Summary

This is a prospective, multicenter observational study to explore the predictive factors of checkpoint inhibitor pneumonitis (CIP) and to establish predictive models by combining imaging information for IRP. The imaging type of CIP, the pathological type, various inflammatory cytokines and tumor proportion score(TPS) of PD-L1 expression level, etc. will be paid more attention.

Conditions

  • Pneumonia, Interstitial

Interventions

OTHER

Immune checkpoint inhibitors(ICIs) therapy

Patients with malignant tumors who first received ICIs

Sponsors & Collaborators

  • Tang-Du Hospital

    collaborator OTHER

  • The First Affiliated Hospital of Zhengzhou University

    collaborator OTHER

  • Henan Cancer Hospital

    collaborator OTHER_GOV

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    collaborator OTHER

  • Fujian Cancer Hospital

    collaborator OTHER_GOV

  • First Affiliated Hospital Xi'an Jiaotong University

    lead OTHER

Principal Investigators

  • Hui Guo, PH.D · First Affiliated Hospital Xi'an Jiaotong University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-20
Primary Completion
2024-02-01
Completion
2025-02-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04734067 on ClinicalTrials.gov