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Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population

NCT04729855 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2025-04-30

No results posted yet for this study

Summary

1. Determination of expression level of HOTTIP and EIF4EBP1(Eukaryotic translation initiation factor 4E-binding protein 1) .
2. Investigation of the SNP HOTTIP rs1859168 and it's association with CRC susceptibility.
3. Correlation of the expression of these genes with various stages of CRC to determine the prognostic value of each of them.

Conditions

  • Colo-rectal Cancer

Interventions

DIAGNOSTIC_TEST

PBMCs and Tissue expression of HOTTIP ,EIF4EBP1 and serum SNP HOTTIP rs1859168

5 ml fresh blood sample, normal and CRC tissue

Sponsors & Collaborators

  • South Egypt Cancer Institute

    collaborator OTHER

  • Esraa Hassan,MD

    lead OTHER

Principal Investigators

  • Esraa H Mohamed, Master · Assistant lecturer of Medical Microbiology and Immunology

Eligibility

Min Age
25 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-15
Primary Completion
2023-05-20
Completion
2024-09-20

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04729855 on ClinicalTrials.gov