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Pupillometry and Somatosensory Evoked Potential in Cardiac Arrest

NCT04720482 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2021-01-26

No results posted yet for this study

Summary

Somatosensory Evoked Potentials (SSEP) and Pupillary Light Reflex (PLR) are key methods for neurologic prognostication in comatose survivors of cardiac arrest. Both methods have low false positive rates.Though they assess different functions of the brain, they should both be sensitive to severe anoxic/ischemic injury from cardiac arrest. The aim of this observational prospective study with an estimated recruitment of 50 patients is to examine the interrelation between PLR and SSEP. PLR will be assessed by Neurological Pupil index (NPi) and SSEP by the cortical N20 response to stimulation of the median nerve.

Conditions

  • Cardiac Arrest
  • Cardiopulmonary Arrest With Successful Resuscitation
  • Resuscitation

Interventions

DIAGNOSTIC_TEST

Somatosensory Evoked Potentials

SSEP performed bilaterally with stimulation of the median nerve

DIAGNOSTIC_TEST

Automated Pupillometry

PLR quantified as NPi using a handheld automated pupillometer

Sponsors & Collaborators

  • Göteborg University

    collaborator OTHER

  • Sahlgrenska University Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-03
Primary Completion
2022-06-30
Completion
2022-06-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04720482 on ClinicalTrials.gov